CIMmultus™是一种新型的、经过改进的预包装色谱整体柱系列,其特点是具有较大的流动通道,用于处理大蛋白(IgG,IgM,聚乙二醇化蛋白即peg化蛋白),病毒(AAV,腺病毒,慢病毒,流感病毒,噬菌体) ,VLPs和pDNA。
由于其性能特点,CIMmultus™色谱柱可用作一次性使用或多次使用的色谱柱。 CIMmultus™的一个重要特征是其外壳; 由环氧热固性材料制成,并用碳纤维加固,使色谱柱具有与不锈钢相同的结构强度。 CIMmultus™色谱柱符合cGMP要求。
QA (quaternary amine) Strong anion exchanger Working range, pH 2–13 Binds molecules with predominantly negative charge, repels molecules a pr…
DEAE (diethylamine) Weak anion exchanger Working range, pH 2–9 Binds molecules with predominantly negative charge, repels molecules a predomi…
SO3 (sulfonate) Strong cation exchanger Working range, pH 2–13 Binds molecules with predominantly positive charge, repels molecules a predominant…
C4 (butyl) high ligand density (HLD) Strongly hydrophobic, uncharged Working range, pH 2–10 Highly effective for removing proteins f…
OH - HIC OH (hydroxy) Uncharged (neutral) ligand Working range, pH 2–10 Retains very large solutes (virus particles, VLP, vesicles) in the prese…
EDA - AEX/Activated EDA (ethylenediamine) Weak anion exchanger Working range, pH 2–9 Binds molecules with predominantly negative charge, repels …
H-Bond ADC H-Bond Multimodal hydrogen donor-acceptor Working range, pH 2–13 Enables size-based separation of product and contaminants at acidic …