Oligo dT - Affinity

Oligo dT {Deoxy Thymine}

 Oligo dT ligands covalently bound to a solid support

 Hybridises to the poly-adenylated tail which is present on most eukaryotic mRNAs, or synthetised onto the molecule during IVT

 Primarily intended for fast and efficient capture and purification of mRNA with a poly-adenylated tail, from various sources

 Can selectively remove impurities from the sample and is a convenient approach for initial purification of mRNA